1. Core Product Specifications

Product Name: TB500 Short Peptide
English Name: TB500 Short Peptide, Thymosin Beta-4 Active Fragment
Alias: Thymosin Beta-4 Short-Chain Active Peptide, TB500 Repair Peptide
CAS No.: 885340-08-9
Core Sequence: Ac-LKKTETQ-OH (Tβ4 17–23 active functional fragment)
Molecular Formula: C??H??N??O??
Molecular Weight: 889.05
Appearance: White lyophilized crystalline powder, odorless, non-caking, uniform color and high purity
Purity: ≥99.0% (Tested by HPLC)
Moisture Content: ≤2.0%
Heavy Metals: ≤10ppm
Endotoxin: ≤0.1EU/mg
Residue on Ignition: ≤0.1%
Solubility: Freely soluble in pure water, sterile buffer solutions and aqueous systems, fast dissolution with clear and stable solution without impurities or precipitation
Storage Conditions: Store powder at 2-8℃ in sealed, dry and dark environment; store prepared solution at -20℃ and avoid repeated freeze-thaw cycles
Production Technology: Solid Phase Peptide Synthesis (SPPS), terminal acetylation modification, multi-stage HPLC precision purification, low-temperature vacuum freeze-drying technology
Product Attribute: Human homologous short-chain active repair peptide, retaining the core repair functions of full-length Thymosin Beta-4
Shelf Life: 24 months under standard sealed and low-temperature storage conditions

2. Professional Product Introduction

TB500 short peptide is the minimum effective active fragment of Thymosin Beta-4 (Tβ4), retaining only the core functional sequence at positions 17–23. It is a benchmark short-chain peptide in the fields of tissue repair, angiogenesis and anti-inflammatory skin care. Different from full-length macromolecular Tβ4, TB500 removes invalid redundant sequences and focuses on three core pathways: actin binding, cell migration and tissue remodeling. It accurately regulates cell movement, endothelial cell differentiation, keratinocyte proliferation and collagen deposition. This product effectively inhibits local inflammatory responses, reduces cell apoptosis, promotes microvascular regeneration, and accelerates soft tissue and epidermal damage repair, while delivering excellent immune regulation performance. Benefiting from its short-chain structure, it features superior biological stability, longer in-vivo half-life and stronger anti-degradation ability compared with long-chain thymosin peptides. It serves as a high-end research-grade core peptide for biomedical mechanism research, tissue injury repair modeling, anti-aging repair formulas and wound repair raw materials.