Professional Product Parameters: CAS 108347-85-9 (NMNH, Reduced β?Nicotinamide Mononucleotide Disodium Salt)

1. Basic Identification

• CAS No.：108347-85-9
• Product Name：Reduced Nicotinamide Mononucleotide Disodium Salt (NMNH)
• IUPAC Name：Sodium ((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate
• Synonyms：NMNH; Reduced NMN Disodium; β?Nicotinamide Mononucleotide, Reduced Form Disodium Salt
• MDL：MFCD12405005

2. Chemical Data

• Molecular Formula：C11H15N2Na2O8P
• Molecular Weight：380.20 g/mol
• Exact Mass：380.0360
• LogP：-3.20 (calculated)
• TPSA：160.25 ?2
• H?Bond Donors：3; H?Bond Acceptors：11
• Rotatable Bonds：5

3. Physical & Chemical Properties

• Appearance：White to off white / pale yellow crystalline powder
• Solubility：Highly soluble in water (>500 mg/mL); soluble in DMSO; slightly soluble in ethanol; insoluble in ether, ethyl acetate, chloroform
• Melting Point：~160–165 °C (decomposition)
• pH (1% aq.)：3.0–5.0
• Stability：Highly sensitive to oxidation, heat, and light; hygroscopic
• Storage：-20 °C (long term); 2–8 °C (short term)

4. Product Specifications

• Purity：≥98% (HPLC); ≥99% (pharmaceutical/food grade)
• Grade：Research grade / Pharmaceutical grade / Food grade
• Typical Packing：100 mg, 500 mg, 1 g, 10 g, 100 g, 1 kg (aluminum foil bag), 25 kg (cardboard drum)
• Moisture：≤1.0%
• Heavy Metals：≤10 ppm; Pb ≤0.5 ppm; Cd ≤2.5 ppm; Hg ≤1.5 ppm; As ≤0.15 ppm
• Sodium Content：11.5%–13.5%
• Residue on Ignition：≤0.5%

5. Biological Function & Applications

• Core Role：Superior NAD? precursor; faster and more potent NAD? booster than NMN (~2–5× higher efficiency); supports cellular energy metabolism, redox balance, DNA repair, and sirtuin activity
• Main Uses：Anti?aging supplements, nutraceuticals, NAD? pathway research, cell culture additives, pharmaceutical intermediates

6. Safety Information

• GHS Classification：Non?hazardous for general transport; no acute toxicity reported
• Handling：Avoid inhalation/skin/eye contact; use in well?ventilated area
• Disposal：Dispose per local chemical waste regulations