1. Core Product Specifications

Product Name: Nicotinic Acid Mononucleotide
Abbreviation: NaMN, β-NaMN
Alias: Nicotinate Ribotide
CAS No.: 321-02-8
Product Type: NAD+ biosynthesis intermediate, cellular metabolic regulator, biochemical research reagent, enzymatic reaction substrate, microbial metabolism raw material
Molecular Formula: C??H??NO?P
Molecular Weight: 335.2 g/mol
Chemical Structure: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate inner salt
Appearance: White to off-white crystalline powder, uniform loose texture, non-caking, odorless with ultra-low impurities
Purity: ≥99.0% (HPLC, research grade / biochemical grade)
Moisture Content: ≤2.0%
Heavy Metals: ≤10ppm
Residue on Ignition: ≤0.1%
Solubility: Freely soluble in pure water and aqueous buffer solutions, slightly soluble in ethanol. The solution is clear, stable and free of precipitation
Transport Condition: Sealed, dry and light-proof transportation at room temperature
Storage Condition: Long-term storage at -20℃ in sealed, dry and dark environment; short-term storage at 2–8℃. Avoid high temperature, humidity and strong light exposure to prevent molecular degradation and activity reduction
Production Technology: Biological enzymatic synthesis technology, high-precision isomer purification, multi-stage HPLC refining, low-temperature vacuum drying activity locking technology
Core Bioactivity: Key intermediate in NAD+ de novo biosynthesis pathway, regulates cellular energy metabolism, participates in microbial and intracellular redox reaction, supports nicotinic acid metabolic cycle research
Shelf Life: 24 months for sealed dry powder stored at -20℃ under standard dry and dark conditions
Usage Restriction: For scientific research, biochemical mechanism experiments and metabolic pathway research only. Strictly prohibited for unauthorized clinical use and illegal applications

2. Professional Product Introduction

Nicotinic Acid Mononucleotide (NaMN, CAS: 321-02-8) is a key intermediate in the intracellular NAD+ de novo biosynthesis pathway and an essential biochemical raw material for nicotinic acid metabolism research. Different from NMN (Nicotinamide Mononucleotide), NaMN is a core precursor substance in the classical NAD+ synthetic route, participating in intracellular redox balance regulation and energy metabolic circulation. It acts as a specific substrate for key synthetases in the NAD+ biosynthesis pathway, effectively promoting endogenous nicotinamide adenine dinucleotide synthesis and maintaining normal cellular metabolic functions. With stable molecular structure, high biochemical activity and excellent water solubility, NaMN is widely used in cell metabolism mechanism research, microbial fermentation metabolic regulation, NAD+ synthetic pathway verification and biochemical enzymatic reaction studies, serving as a fundamental and core tool reagent in metabolic biology research.

3. Product Description

This product is high-purity biochemical/research-grade Nicotinic Acid Mononucleotide (NaMN) crystalline powder, produced by mature biological enzymatic synthesis process. It adopts strict structural screening and high-precision purification technology to ensure complete compliance with the standard chemical structure of CAS 321-02-8, with no isomer impurities, synthetic residues or heterologous contaminants. Multi-stage high-precision preparative HPLC deep refining removes reaction by-products and miscellaneous impurities, ensuring stable HPLC purity above 99.0% with excellent batch consistency and experimental repeatability. Featuring accurate molecular configuration and stable biochemical activity, the product can specifically participate in intracellular NAD+ de novo synthesis metabolism without non-specific interference. It strictly controls heavy metals, ash and moisture indicators, with ultra-low impurity content and excellent biocompatibility. It is fully applicable to cellular metabolic pathway verification, microbial metabolism regulation experiments, enzymatic reaction mechanism research and high-standard biochemical testing, meeting dual strict standards of professional scientific research and biochemical reagent production.

4. Core Product Advantages

1. Standard NaMN Structural Purity, No NMN Confusion
Strictly conforms to the official CAS 321-02-8 standard structure of Nicotinic Acid Mononucleotide, with pure target configuration and no invalid isomers or NMN mixed impurities, ensuring accurate and exclusive experimental targeting.

2. Core NAD+ De Novo Synthesis Intermediate
Serves as an indispensable key substrate in the classical NAD+ biosynthesis pathway, stably participates in cellular nicotinic acid metabolic circulation, and effectively regulates intracellular energy metabolism and redox balance.

3. Green Enzymatic Synthesis with High Biocompatibility
Adopts green biological enzymatic synthesis process, free of harmful chemical solvent residues, with stable properties and low non-specific irritation, suitable for long-term cell and microbial metabolism intervention experiments.

4. Professional Metabolic Research Target with Clear Mechanism
The NaMN-mediated NAD+ de novo metabolic pathway is clearly defined with abundant authoritative literature verification. It is the standard core reagent for nicotinic acid metabolism and synthetic biology research with high academic recognition.

5. High Purity & Stable Batch Consistency
HPLC purity ≥99.0% with strictly controlled impurity indicators and stable biochemical activity. Uniform batch quality ensures accurate experimental data and reliable repeatability for metabolic mechanism research.