1. Core Product Specifications

Product Name: L-Ergothioneine
Alias: EGT, 2-Mercaptohistidine Betaine
CAS No.: 497-30-3
Product Type: Natural chiral amino acid, exclusive cytoprotective antioxidant, high-end anti-aging cosmetic raw material, food antioxidant additive, scientific research biochemical reagent
Molecular Formula: C?H??N?O?S
Molecular Weight: 229.30 Da
Appearance: White to off-white crystalline powder, uniform and loose texture, non-caking, odorless with ultra-low impurities
Purity: ≥99.0% (HPLC, Cosmetic/Food/Research Grade)
Moisture Content: ≤2.0%
Heavy Metals: ≤10ppm
Residue on Ignition: ≤0.1%
Solubility: Highly soluble in pure water and aqueous buffer solutions, slightly soluble in partial organic solvents. Aqueous solution exhibits excellent stability with no oxidation or precipitation
Melting Point: 275–277℃ (Decomposition)
Transport Condition: Sealed, dry, light-proof and moisture-proof transportation at room temperature
Storage Condition: Long-term dry powder storage at -20℃ in sealed, dry and dark environment; short-term storage at 2–8℃. Avoid strong light, high temperature and strong oxidation environments. Featuring superior oxidation resistance compared with conventional antioxidants, it remains stable under normal storage conditions
Production Technology: Microbial fermentation purification, chiral resolution purification, multi-stage high-precision HPLC refining, low-temperature vacuum drying activity locking technology
Core Bioactivity: Targeted high-efficiency antioxidation, free radical scavenging, photoaging resistance, mitochondrial and DNA protection, anti-inflammation and soothing, melanin inhibition, skin barrier repair, long-term cellular protection
Shelf Life: 24 months for sealed dry powder stored at -20℃ under standard dry and dark conditions
Usage Restriction: For scientific research, cosmetic formula development and food antioxidant application only. Strictly prohibited for human clinical injection and illegal use

2. Professional Product Introduction

L-Ergothioneine (CAS: 497-30-3, EGT) is a rare natural chiral sulfur-containing amino acid specifically absorbable by the human body, ranking as a top-tier stable and safe high-end active raw material in anti-oxidation and anti-photoaging fields. Unlike oxidizable conventional antioxidants such as Vitamin C and glutathione, L-Ergothioneine possesses a unique stable thiol molecular structure, maintaining stable activity without oxidation failure in aqueous solutions and room-temperature environments, delivering long-lasting antioxidant efficacy. The human body has a specific OCTN1 transporter protein that selectively enriches L-Ergothioneine in high-metabolism and high-oxidative-stress tissues including the skin, liver and kidneys. It precisely scavenges intracellular free radicals, protects mitochondria and DNA from oxidative damage, and effectively relieves skin redness, dullness and photoaging caused by ultraviolet radiation. With excellent anti-inflammatory soothing, melanin inhibitory and barrier repair properties, as well as non-toxicity, non-irritation and superior biocompatibility, it is widely applied in high-end anti-aging and whitening skincare products, functional repair formulas, food anti-oxidation preservation and cellular protection mechanism research.

3. Product Description

This product is high-purity food/cosmetic/research-grade L-Ergothioneine crystalline powder, manufactured via patented microbial fermentation combined with high-precision purification technology. It features pure chiral structure without racemic impurities or synthetic residues, fully compliant with the official standard substance structure of CAS 497-30-3. Multi-stage preparative HPLC deep refining thoroughly removes fermentation impurities, metabolic by-products and isomers, ensuring stable HPLC purity above 99.0% with uniform batch purity, consistent activity and excellent repeatability in formulas and experiments. Featuring a unique thermodynamically stable structure, its irreversible antioxidant capacity solves the common defects of traditional antioxidants such as easy oxidation, short half-life and unstable efficacy. With strictly controlled heavy metals, residues and impurity indicators, the product is non-toxic, non-allergenic and non-cytotoxic with high biological safety. It is fully applicable to skin photoaging experiments, cellular oxidative stress models, antioxidant mechanism research, high-end whitening and anti-aging cosmetic formula development, and food preservation and anti-oxidation R&D, meeting dual strict standards for commercial production and scientific research.

4. Core Product Advantages

1. Ultra-Stable Antioxidant Performance Without Inactivation Risk
The unique stable thiol structure maintains high activity at room temperature, under light exposure and in aqueous solutions. Its durable antioxidant capacity is far superior to VC, lipoic acid, glutathione and other traditional raw materials, ensuring long-term formula stability and reliable experimental data.

2. Human Targeted Absorption for Deep Cellular Protection
Specifically enriched in skin cells via human endogenous OCTN1 transporters. It eliminates free radicals at the cellular level, protects mitochondria and DNA, and repairs oxidative damage, delivering precise and penetrating anti-aging and anti-photodamage efficacy.

3. Multi-Functional Integration for High-End Formula Adaptation
Integrates anti-oxidation, anti-photoaging, anti-inflammation soothing, whitening & melanin inhibition, barrier repair and cellular anti-damage effects. It comprehensively improves skin dullness, fine lines, redness, photodamage and pigmentation, perfectly suitable for high-end premium skincare formulas.

4. Natural Homologous & Ultra-Safe for All Skin Types
Derived from natural microbial fermentation and compatible with human endogenous substances. With extremely low sensitization, no irritation and no toxic side effects, it is safe for sensitive and fragile skin, serving as a compliant raw material for high-end skincare and food additives.

5. High Purity & Strict Quality Control with Excellent Batch Stability
HPLC purity ≥99.0% with no miscellaneous peaks, invalid isomers or process residues. All quality indicators meet strict standards with consistent batch efficacy, fully supporting high-end formula mass production and high-precision scientific research experiments.