1. Core Product Specifications

Product Name: GHK Tripeptide-1
Full Name: Glycyl-Histidyl-Lysine
CAS No.: 49557-75-7
Amino Acid Sequence: Glycyl-L-Histidyl-L-Lysine (GHK)
Peptide Type: Natural active tripeptide, skin repair peptide, anti-aging & anti-inflammatory cosmetic raw material, scientific research biochemical reagent
Molecular Formula: C??H??N?O?
Molecular Weight: 340.38 Da
Appearance: White to off-white lyophilized crystalline powder, uniform loose texture, non-caking, odorless with ultra-low impurities
Purity: ≥98.0% (HPLC, research grade / cosmetic grade)
Form: Pure monomer tripeptide, commercial stable specification (copper-free)
Moisture Content: ≤2.0%
Heavy Metals: ≤10ppm
Endotoxin: ≤0.1EU/mg
Residue on Ignition: ≤0.1%
Solubility: Freely soluble in pure water, normal saline and aqueous cosmetic buffer systems, forming clear and stable solutions without precipitation
Transport Condition: Sealed, dry and light-proof transportation at room temperature
Storage Condition: Long-term dry powder storage at -20℃ in sealed, dry and dark environment; short-term storage at 2–8℃. Dissolved solutions must be aliquoted and frozen. Strictly avoid repeated freeze-thaw cycles to prevent activity attenuation
Production Technology: Standard solid-phase peptide synthesis (SPPS), precise GHK full-length sequence assembly, multi-stage high-precision HPLC purification, low-temperature vacuum freeze-drying activity locking technology
Core Bioactivity: Skin barrier repair, collagen regeneration, anti-inflammatory & antioxidant, anti-wrinkle & firming, wound healing promotion, scalp repair regulation, anti-aging
Shelf Life: 24 months for sealed dry powder stored at -20℃ under standard conditions
Usage Restriction: For scientific research, skin pharmacological experiments and cosmetic raw material development only. Strictly prohibited for human clinical treatment and illegal use

2. Professional Product Introduction

GHK Tripeptide-1 (CAS: 49557-75-7) is a natural high-activity endogenous tripeptide widely present in human plasma and tissues, serving as a classic skin-repairing and anti-aging polypeptide. Different from synthetic functional peptides, pure GHK tripeptide features high human homology and mild activity. It can effectively activate skin fibroblast activity, significantly promote collagen and elastin synthesis, accelerate the repair of damaged epidermal and dermal tissues, and relieve mild skin inflammatory responses. Meanwhile, it scavenges free radicals, improves skin oxidative aging, enhances skin elasticity and fineness, and fades fine lines and dull complexion. With mild properties, excellent skin compatibility and multi-dimensional skin care efficacy, copper-free GHK Tripeptide-1 is widely used in mild repair, sensitive skin care and anti-aging cosmetic development, as well as skin aging mechanism and epidermal repair scientific research.

3. Product Description

This product is high-purity research and cosmetic-grade copper-free GHK Tripeptide-1 lyophilized powder. Adopting mature and rigorous solid-phase peptide synthesis technology, it achieves accurate full-length assembly of the Glycyl-Histidyl-Lysine tripeptide sequence, with complete structural specification, no mis-sequences, truncated defects or extra group modification, fully matching the official CAS 49557-75-7 standard substance structure. Multi-stage high-precision preparative HPLC thoroughly removes synthetic residues, intermediate impurities and process by-products, ensuring stable HPLC purity above 98.0% and excellent batch-to-batch consistency. The pure monomer GHK structure retains complete inherent biological activity of the tripeptide, effectively promoting skin tissue regeneration and anti-oxidative repair without copper ion stimulation, making it safer for sensitive skin research and formula application. With ultra-low cytotoxicity, non-irritating and excellent biocompatibility, the product is fully suitable for in vitro skin cell repair experiments, epidermal anti-aging models, inflammatory skin mechanism verification and mild cosmetic formula R&D, meeting dual standards of scientific research testing and commercial raw material production.

4. Core Product Advantages

1. Pure Monomer Structure Without Copper Stimulation
Adopts pure GHK tripeptide monomer structure, no copper ion complexation, avoiding metal irritation and oxidation sensitization risks. The activity is mild and stable, suitable for sensitive skin research and low-irritation cosmetic formula development.

2. Multi-dimensional Repair & Anti-Aging Efficacy
It integrates collagen regeneration, anti-oxidation, anti-inflammation, wound healing and skin firming effects. It can improve aging problems such as dullness, sagging and fine lines from multiple dimensions, with wide application value in mild repair and anti-aging fields.

3. Natural Homologous & Ultra-Mild Properties
Derived from human endogenous active peptide components, with extremely low immunogenicity and no skin irritation. It has excellent affinity with human skin tissues, safe and reliable for long-term intervention experiments and daily skin care applications.

4. Mature Research & Wide Application Prospects
As a classic endogenous repair tripeptide, it has abundant authoritative literature and application verification. The action mechanism is clear and the efficacy is stable, suitable for high-end skin pharmacology research and mild anti-aging cosmetic raw material development.

5. High Purity & Stable Batch Consistency
HPLC purity ≥98.0% with strictly controlled impurity residues and stable monomer activity. Uniform batch quality ensures accurate experimental data and consistent cosmetic formula efficacy.