Product
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DSIP（Delta Sleep-Inducing Peptide）
- Brand：MAINTAIN
- Model：1G,10G,1KG,5KG,25KG
- Purity：98%
- Cas：62568-57-4
- Createtime： 2026-07-02
- Updatetime： 2026-07-16
Product Details
| useage | FOR R&D RESEARCH USE |
| deliveryInfo | |
| appearance | white to off white powder |
| aliasen | |
| supplyCapacity | 5000000KG/Year |
| harbor | SHENZHEN |
| minorder | 1G |
Delta Sleep-Inducing Peptide (DSIP / Emideltide) CAS 62568-57-4
1. Basic Chemical Information
- CAS No.: 62568-57-4
- Full Name: Delta Sleep-Inducing Peptide
- Short Name: DSIP, Emideltide
- Peptide Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)
- IUPAC Name: L-Tryptophanyl-L-alanyl-glycyl-glycyl-L-aspartyl-L-alanyl-L-seryl-glycyl-L-glutamic acid
- Synonyms: Sleep-regulating nonapeptide, Anti-stress cosmetic peptide, δ-Sleep Inducing Peptide
- Molecular Formula: C??H??N??O??
- Molecular Weight: 848.81 g/mol
- MDL No.: MFCD00076883
- EINECS: 214-667-9
2. Physical & Chemical Properties
| Test Item | Standard Specification |
|---|---|
| Appearance | White to off-white lyophilized crystalline powder |
| Odor | Odorless |
| Solubility | Freely soluble in purified water, neutral PBS buffer; soluble in glycerin & DMSO; slightly soluble in ethanol; insoluble in mineral oil, acetone, ether |
| pH (0.1% aqueous solution) | 4.0 ~ 6.8 |
| Predicted Boiling Point | 1522.7±65.0 °C |
| Density | 1.458±0.06 g/cm3 |
| Thermal Stability | Add below 45℃ during emulsification; avoid sustained heating above 60℃ |
| Stability | Stable under weak acid & neutral cosmetic systems; incompatible with strong alkali, high-concentration oxidants, long-term UV exposure |
| Hygroscopicity | Moderately hygroscopic; vacuum nitrogen-sealed storage required |
3. Quality Specifications (Cosmetic & Research Grade)
| QC Item | Standard Limit | Test Method |
|---|---|---|
| Assay (HPLC, anhydrous basis) | ≥98.0%; Premium ≥99.0% | RP-HPLC UV 220 nm |
| Loss on Drying (KF) | ≤0.50% | Karl Fischer Titration |
| Residue on Ignition | ≤0.10% | Gravimetry |
| Single Unknown Related Impurity | ≤0.30% | HPLC |
| Total Related Impurities | ≤1.00% | HPLC |
| Free Amino Acid Residue | ≤0.10% | HPLC |
| Endotoxin | ＜50 EU/mg | LAL Test |
Heavy Metals
Lead (Pb) ≤0.5 ppm; Arsenic (As) ≤1.0 ppm; Cadmium (Cd) ≤0.1 ppm; Mercury (Hg) ≤0.1 ppm
Microbial Limits
Total Aerobic Microbial Count ≤500 CFU/g; Yeast & Mold ≤50 CFU/g; E. coli, Salmonella, S. aureus Negative per 25g
4. Core Biological Mechanism & Efficacy
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Regulate Neuroendocrine & Relieve Skin Stress (Core Cosmetic Effect)
Biomimetic endogenous sleep neuropeptide; reduces cortisol secretion in skin cells induced by staying up late, screen radiation and mental stress, alleviates stress-induced skin aging (stress aging).
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Anti-Inflammaging & Calming Sensitive Skin
Inhibits release of inflammatory cytokines TNF-α, IL-6, scavenges ROS free radicals, relieves facial redness, irritation and dullness caused by stress and UV damage.
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Repair Skin Barrier & Restore Radiant Skin
Stimulates fibroblast activity, upregulates collagen I and hyaluronic acid synthesis, improves rough, dry, sagging and tired matte skin texture.
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Anti-Dark Circle & Periorbital Edema Auxiliary Improvement
Improves microcirculation around eyes, relieves dark circles and puffiness caused by long-term lack of sleep and stress, synergistic with Acetyl Tetrapeptide-5 (Eyeseryl).
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Improve Sleep-Associated Skin Regeneration
Simulates skin night repair state, accelerates epidermal cell renewal, strengthens skin self-repair capacity overnight, widely used in night repair skincare series.
5. Application Fields & Recommended Dosage
5.1 Night Repair Anti-Stress Skincare (Core Application)
Overnight repair serum, sleep mask, anti-fatigue brightening lotion, stress recovery nourishing cream
- Recommended addition: 0.001% ~ 0.08% (w/w)
5.2 Eye Contour Care
Anti-puffiness eye gel, dark circle repair eye cream, tired eye relief essence
- Recommended addition: 0.001% ~ 0.05% (w/w)
5.3 Sensitive & Post-Sun Calming Products
Soothing repair lotion, UV damage recovery cream, redness relief essence
- Recommended addition: 0.001% ~ 0.03% (w/w)
Formula Operation Tips
Optimal formulation pH range: 4.0–6.5; compatible with hyaluronic acid, panthenol, acetyl tetrapeptide-5, vitamin E derivatives; add at low-temperature late emulsification stage.
6. Safety Profile
- Non-irritating to facial skin and delicate ocular mucosa at standard cosmetic dosage
- Non-sensitizing, non-phototoxic, no contact allergy risk
- Natural endogenous regulatory peptide in human body, excellent biocompatibility with keratinocytes and fibroblasts
- No cytotoxicity under routine leave-on cosmetic concentration
7. Storage & Packaging
- Storage Condition: Hermetic nitrogen-filled aluminum foil vacuum bag; long-term storage at -20°C, strictly light-proof & moisture-proof; avoid repeated opening and freeze-thaw cycles; short-term storage ≤4°C
- Shelf Life: 36 months under intact original vacuum packaging
- Packaging: 1g/5g aluminum vacuum foil bags for cosmetic factories; 25kg double PE inner bag + paper drum for bulk orders
