1. Core Product Specifications

Product Name: Thymosin β4
Full Name: Thymosin Beta 4 Acetate
CAS No.: 77591-33-4
Peptide Length: Full-length 43-amino acid polypeptide
Peptide Type: Endogenous multifunctional active polypeptide, actin-binding peptide, tissue repair peptide, immune regulatory peptide, pharmaceutical intermediate for scientific research
Molecular Formula: C???H???N??O??S
Molecular Weight: 4963.49 Da
Appearance: White to off-white lyophilized crystalline powder, loose and uniform texture, non-caking, odorless with ultra-low impurities
Purity: ≥98.0% (HPLC, research grade / pharmaceutical grade)
Form: Acetate salt (mainstream stable commercial specification)
Moisture Content: ≤2.0%
Heavy Metals: ≤10ppm
Endotoxin: ≤0.1EU/mg
Residue on Ignition: ≤0.1%
Solubility: Freely soluble in sterile purified water, normal saline and weakly acidic buffer systems, forming clear, stable and precipitate-free solutions
Transport Condition: Sealed and light-proof transportation at room temperature
Storage Condition: Long-term dry powder storage at -20℃ in sealed, dry and dark environment; short-term storage at 2–8℃ for 1–2 weeks. Dissolved solution must be aliquoted and frozen. Strictly avoid repeated freeze-thaw cycles to prevent structural and activity inactivation
Production Technology: Standard solid-phase peptide synthesis (SPPS), precise full-length 43-amino acid assembly, multi-stage high-precision HPLC purification, low-temperature vacuum freeze-drying activity locking technology
Core Bioactivity: Bidirectional immune regulation, tissue damage repair promotion, anti-inflammation and anti-oxidation, cell migration and proliferation regulation, anti-fibrosis, angiogenesis promotion, wound healing
Shelf Life: 24 months for sealed dry powder stored at -20℃ under standard conditions
Usage Restriction: For scientific research, biochemical experiments and preclinical drug development only. Strictly prohibited for human clinical treatment, cosmetic application and illegal use

2. Professional Product Introduction

Thymosin β4 (CAS: 77591-33-4) is an endogenous 43-amino acid multifunctional active polypeptide widely present in human tissues and one of the most well-studied actin-regulating tool peptides in scientific research. It efficiently binds and sequesters cellular actin, precisely regulating cytoskeleton remodeling, cell migration and cell proliferation. It possesses multiple potent biological activities including tissue repair, anti-inflammatory, antioxidant and immune-modulating effects. Thymosin β4 effectively accelerates the repair of skin wounds, mucosa, blood vessels and soft tissue injuries, inhibits excessive inflammatory infiltration and tissue fibrosis, and balances immune homeostasis to improve local microenvironments. Featuring extremely low immunogenicity, excellent biocompatibility and broad-spectrum regenerative capabilities, it is widely applied in wound healing mechanism research, skin regenerative medicine, anti-inflammatory pharmacology, immune regulation experiments, anti-fibrosis studies and preclinical new drug development.